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Use the interchange search on car-part.com when initially looking into these things. If not, then there are sometimes small variances. For Example, my cousin totaled his Durango with a 4.7L. I took it for my Jeep but the only difference was the oil pan and pickup.
Does anyone know for sure if an engine out of a 97 C1500 will interchange with a 99 GMC Safari mini van?