It depends on what kind of sound you want. A sealed box hits low, more consist, and clearer bass, and a ported box will be louded, but not as clean sounding.
What are the 12s? If you don't have the manaul for them, you can find most manauls for subs anywhere on the net. The manaul should say how big the box should be to port it and what your cons and pros are. I'd stick with sealed, but thats my preference.