I've done it several times with good results. I'm in the parts gathering stages of a turbo 6.0 swap in my 84K20. The main things you need to ask yourself is what is your budget? carb or EFI? What do you use the truck for? 10psi will make a stock 350 haul the mail, but you'll spend a minimum of $3K if you can do the fan work and tuning yourself if you don't use junk parts. You can do it with Chinese stuff cheaper, in fact, that's what I'm doing on my 6.0, but we'll have to wait to see how that shakes out.
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