I don't think you will be able to tell by jacking it up and seeing which side lands first...there are weight differences, gas tank, trans weight, transfer case if 4x4, steering box weight, steering column, etc...
It may be the rubber bushings at the bed bolts. If those bushings are compacted or dryrotted, that may show a difference in how it looks.
Does the bed look out of alignment with the cab? Do the design mouldings and indentations line up (from front fender, door, and bed)? If it was spring related, the cab and bed will still look aligned to themselves, just a corner of the truck will sit lower. If it was the bed bolts/bushings, or frame bent, I would think it would be apparent by misalignments of the bed to the cab. There may even be more of a gap between the cab and bed on one side or top/bottom.