Welcome to the site.
From the factory, the Vortec 350's (in my opinion) were pretty stout engines in stock form. You have a '98 model drivetrain, so if it is bone stock and never reconditioned, you could just need to address issues with the factory systems first.
To get a baseline for your question, is the engine a stock '98 Vortec 350 w/the vortec heads, fuel injection, etc? Do you know the condition of the engine (compression on all cylinders & difference in compression between cylinders), ignition system condition & fuel system (pump, injectors)?
As far as upgrades do you want top end power or bottom end torque? Torque is what gets you moving.
A few performance oriented upgrades that do not require pulling apart the engine: Headers, free flowing exhaust and a performance chip.