Your only 4 big bolts, shift linkage, speedo cable & a few wires from doing it once it's stripped of the "regular" bolt-on stuff...That is the easy part.
The biggest obstacle for the average guy is lifting/supporting the cab. You just have to be creative (but SAFE!) & use whatever means you have available. If you have a way to do that, it's a piece of cake from there. Jacking & blocking then letting down the frame (removing the front tires & rolling on bare wheels?) can work well if you have access to a bunch of wooden blocks & some sturdy jackstands. However, now you can't easily work on the bottom of the cab. A forklift, skidloader, backhoe, ect. can be used for lifting.
Something I've done several times is to unbolt & lay the cab back on the frame (blocking it up at the top of the rear window opening so the back panel doesn't get bent)...this way you can clean & paint the front of the frame & bottom of the cab, then put it back up, then do the rear of the frame. This is a great way if you don't really have the means to lift or block the cab or the space to have everything separate & is much safer & easier then a bunch of blocks. Have Fun! Lorne