DnStClr is Correct, get to cleaning that Poor Ol' Quadra-Bowl(Big Mouth 4 Barrel that likes to suck gas, when it looks in that bad of shape), and do a Full Rebuild on it.... Adjusting it won't get you anywhere near where it should be, after it has been properly rebuilt (They are some of the easiest Carbs to Rebuild, its just getting the float at the proper setting that takes patience)......
Yes there is adifferent adjustment for a "High Altitude" and "Low Altitude" Carb, so if you try driving a Vehicle with the incorrect adjustment, it would be like it was sucking a through a stir-stick straw, rather than a good sized regular straw(Starving for Air, if it is adjusted for a Lower Alt, or Getting too Much Air if adjusted for a Higher Alt, and used in a Lower Alt)......