do you want to have this as a dedicated mudder, or more of a trail truck that can romp in the mud? If it's the latter, what kind of trails are you running? The last factor that determines the build is how often (if at all) the truck will get driven on the street.
The good news (as others have pointed out) is that you already have some pretty stout running gear under the truck.
A couple things you should do regardless of how the truck is going to be used is to beef up your cooling system and to strengthen the frame around the steering box area.
A good recipie for a mud truck is big axles (which you've got), big power, and big tires. Throw a set of 38" Boggers on some beadlocks (with some judicious fender trimming), 4.88's in the axles, weld up the rear diff and a detroit in the front, and a 100 shot of nitrous if you're planning on going through the big pits. Suspension articulation is not a huge concern on a truck like this, so a pair of beefy traction bars on the rear axle wouldn't be out of place.
As for a trail truck, I'm going to assume some rock crawling, some dune running, and a bit of mud whumping every so often. Since crawling over obstacles with a fullsize very often involves dragging the truck itself over obstacles, protection is needed. Start by fabbing some skidplates for your tranny and T case. A rock ring for the fron t axles would not be out of the question, and shaving the bottom of the corporate 14 bolt is an old and proven rock crawler trick. A good, high clearance bumper is almost a necessity. You may also consider replacing the bed or bobbing it for a better departure angle. Rocker protection would be nice, but not a necessity.
A set of 36's on steel beadlocks would be good. Stuffing the pumpkins with 4.56's and using a spool or Detroit in the rear would be good, as would an ARB or Ox locker in the front.
As far as the suspension goes, your 4 inch lift is a good size, but you have to make sure it flexes. Using longer springs along with relocating the hangers and perches would give you the same lif you have now but would allow you to have a flatter spring pack, which usually gives you more flex. A sway bar disconnect system would furhter enchance the front end flex. For the rear, a shackle flip and longer springs would again give you more flex with a flatter pack. ORD makes some good heavy duty greasable shackles for the fron t and rear along with beefed up braketry for the springs that really enhance performance.