I have installed a few, once on a 67 Camaro and on a Toyota but not on my truck just yet . . .
However, the concept is the same. The remote lock motor pushes and pulls the rod that is on the other end of the door lock knob so it has to be freely moving. Most kits attach to the rod with a clamp - make sure the clamp is aligned and tightly clamped down and that the lock motor is aligned with the rod that moves the lock.
If your truck doesn't have an existing hole for wiring you'll need to take your time and think about the best placement for the wiring to pass from the kick panel area to the door. You'll have to drill a few holes - take the time to smooth the holes out, paint them, grommet them, and use wireflex or loom to protect the wiring. Other than that - most kits use Bosch relays and they are common parts to replace if anything does fail.