The Frame Rails are the same, everything that is riveted to them are not the same short of the body mounts.
None of the holes are in the 4x4 frame for 2WD set. If you look at my 1989 Blazer built I converted it from 4X4 to 2WD.. Also, the forward mounts on the 4x4 are different as they have the leaf perch built in, but it will work..