You don't need to reflash the computer just remove the security out of it. I don't see the need in buying another computer when the factory one is designed to last hundreds of thousands of mines.
Are you planning on just getting the motor or a trans also. Keep in mind after 1988 on C/K (not our bod style) the transfer case drop in on the opposite side, so you will have to use a transfercase that you currently have bolted to a 4L60E or get one. If you already have a good trans the LS will bolt to it, you just need to provide a TV cable.
You will need motor mounts also.