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Obviously, on a totally stock engine, namely a 305, you don't want to get to crazy with the boost; i'm thinking (will do more research) 14lbs in very occasional short spurts would be ok if we assume a stock compression ratio of 7.5 to 1. Up to 7lbs should be ok all the time.i think high RPM is way more detrimental than pressure on the pistons/rods/crank etc.Will clarify further later; Too tired now.
Put a 302 in one of our trucks and you probably wouldn't be too happy with it.