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Did you check your fuel pressure? Do you have a scan tool?
Fuel Gauge: Bottom of this page, it mounts where the gauge hooks up normally. http://hotrodlane.cc/08%20catalog/page%2062.pdfDid you wire in a light to the diagnotics (psuedo Check engine light)?
What happens when you punch it hard? I mean lay into it... Does it stumble really hard?How far is that O2 sensor from the headers? If it is too far, you'll need a heated 02 possibly if it doesn't get hot enough. Does it smoke black or anything else odd?
How many lb. injectors are you running? Is it a stock setup from a 350 TPI originally? If you've modded the cam and gone with more flow inside that motor the stock donor 350 fuel pump won't keep up either. Need at least a 255 liter per hour. (If I'd read every shred of the post here I am sure you've addressed this already so my apologies if being redundant).